Vacancy expired!
Janssen
Research & Development, L.L.C., a division of Johnson & Johnson's
Family of Companies, is recruiting for a Principal Scientist in our Analytical Chemistry
– Discovery Chemistry, located in La Jolla, CA (San
Diego area).At the
Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to
create a world without disease. Transforming lives by finding new and better
ways to prevent, intercept, treat and cure disease inspires us. We bring
together the best minds and pursue the most promising science.We are
Janssen. We collaborate with the world for the health of everyone in it. Learn
more at www.janssen.com and follow us @JanssenGlobal. Janssen
Research & Development, LLC is part of the Janssen Pharmaceutical
Companies.This position will require the candidate
to possess and apply extensive knowledge and skills in Analytical and
Separation Sciences in order to provide a streamlined and impactful analytical
support to accelerate Janssen Discovery pipeline. The ideal candidate must have
extensive hands-on experience with high-resolution NMR spectroscopy, including
1D & 2D NMR data interpretation along with experimental set-up and problem
solving, and extensive experience on LC/MS instrumentation and data
interpretation in supporting Discovery Chemistry. In addition, the candidate
must have up-to-date knowledge on frontier analytical chemistry capabilities
and their applications in drug discovery. Responsibilities will include:
Oversee analytical chemistry staff and operation for
the La Jolla site.
Together with other members of the group, evaluate and
implement new NMR and LC/MS methods and new ways to apply these
technologies for Discovery Chemistry support.
Work with the vendor, when necessary, to maintain and
repair spectrometers.
Communicate results of analytical studies to chemistry
project teams and review data generated by fellow analytical chemistry
staff.
Present results at internal project meetings and at
external scientific meetings as appropriate.
Routinely interact with scientists from medicinal chemistry
teams to develop and implement strategies to help advance programs
Evaluate the scientific literature critically and adopt
novel technologies which will facilitate analytical support. Assist in
setting scientific direction for team.
Qualifications
Education requirements include a Ph.D. in chemistry,
biochemistry or related discipline with minimum 5 years of applicable
post-graduate experience is required.
At least 4 years pharmaceutical industry experience
with a track record in application of Analytical Chemistry is required.
The use of routine and advanced NMR methods to
characterize synthetic medicinal compounds for structure and purity
determination is required. (This includes in depth knowledge of Bruker NMR
spectrometers, maintenance, troubleshooting, automation, pulse
programming, and method development.)
Extensive experience with NMR software for data
acquisition and interpretation, may include but not limited to TopSpin,
ACDLabs and/OR MestReNova, is required.
Experience in high throughput NMR methods is preferred
A strong background in synthetic organic chemistry is
also preferred.
Hands-on experience using LC/MS methods for
characterization of medicinal compounds is also required.
Use of Agilent and Waters LC/MS systems and software is
preferred.
Familiarity with techniques to determine
stereochemistry and absolute configuration is required.
A significant scientific publication record and a
history of excellent communication and collaborative approach is required.
Prior people management experience is strongly preferred.
This position is located in La Jolla, CA, and may
require up to 15% travel.
Johnson & Johnson is an
Affirmative Action and Equal Opportunity Employer. All qualified applicants
will receive consideration for employment without regard to race, color,
religion, sex, sexual orientation, gender identity, age, national origin, or
protected veteran status and will not be discriminated against on the basis of
disability.Primary LocationUnited States-California-San Diego-Other LocationsNorth America-United States-California-La JollaOrganizationJanssen Research & Development, LLC (6084)Job FunctionChemistryRequisition ID6625191004
Vacancy expired!