Vacancy expired!
Janssen Research & Development,
L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting
for a “Scientist, PET Tracer Discovery”, located in San Diego, CA.At the Janssen Pharmaceutical Companies
of Johnson & Johnson, we are working to create a world without disease.
Transforming lives by finding new and better ways to prevent, intercept, treat
and cure disease inspires us. We bring together the best minds and pursue the
most promising science. We are Janssen. We collaborate with the world for the
health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal. Janssen Research
and Development, LLC is part of the Janssen Pharmaceutical Companies.The
PET imaging group at Janssen is committed to the discovery and validation of Positron
Emission Tomography (PET) imaging agents for a number of different targets supporting
all Therapeutic Areas (TAs). Our diverse
team requires deep scientific expertise in many disciplines including chemistry,
radiochemistry, cellular and molecular pharmacology, enzymology, and imaging
technologies coupled with an ability to work collaboratively with internal and
external partners. We are currently
seeking an outstanding individual to join our team as Scientist,
PET Tracer Discovery. This
position will focus on lead discovery and optimization chemistry, and will be
based at our site in San Diego, CA.We are seeking a Senior level PhD Chemist
with excellent synthetic organic synthesis and/or medicinal chemistry expertise
to advance small molecule drug discovery leads into clinical PET tracers. In this laboratory-based position, the
successful candidate will partner with both internal and external medicinal
chemistry teams to generate small molecule imaging agents. She/he will maintain close interactions with discovery
scientists, computer assisted design scientists, biologists, pharmacologists,
and imaging specialists. Strong people
skills and the ability to thrive in a team and goal driven environment are key
attributes. Responsibilities of the Senior Scientist,
PET Chemistry, include:
Developing and executing clear synthetic
strategies towards complex molecules using state-of-the-art synthetic
methodologies.
Independently designing and synthesizing
drug-like molecules utilizing medicinal chemistry knowledge and an
understanding of ADME, pharmacokinetics and physicochemical properties optimal
for PET imaging agents
Synthesis of PET labeling precursors and cold standards
and optimization of labeling and purification conditions
Collaboratively supporting the advancement of
compounds through in vitro and in vivo studies to identify development
candidates
Collaboration with structure-based design
groups to impact rational design of molecules.
Contributing to defining scientific strategies
and goals within a project team setting
Presenting data and reports on project status
at individual, group, and departmental meetings
Drafting, executing and serving as lead author
on research published in peer reviewed journals, and presenting work at
scientific conferences
This individual must also excel in
communication and have strong interpersonal skills necessary to influence in a
collaborative multidisciplinary environment.
Qualifications
A minimum of PhD degree
in synthetic, organic or medicinal chemistry is required
At least 3 years
of postdoctoral and/or industrial experience with
good track record of peer-reviewed publications is required
Experience in the design, and synthesis of
complex molecules and synthetic methodology development, with deep knowledge of
modern synthetic & analytical techniques, including click chemistry, is
required
Proficient in use of laboratory instruments including LC/MS, NMR,
preparative HPLC purification is required
Knowledge of PET imaging and understanding of methods
for introducing fluorine into organic molecules is a plus.
A proven track record of scientific
contributions including peer reviewed publications, patents and presentations
is required
Independent thinking and the ability to
effectively collaborate in a highly matrixed environment are required.
Excellent oral and written communication
skills, including preparation of presentations are required
This position is located in La Jolla, CA, and requires a minimum 90% of time spent in the lab.
Johnson &
Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified
applicants will receive consideration for employment without regard to race,
color, religion, sex, sexual orientation, gender identity, age, national
origin, or protected veteran status and will not be discriminated against on
the basis of disability.Primary LocationUnited States-California-San Diego-Other LocationsNorth America-United States-California-La JollaOrganizationJanssen Research & Development, LLC (6084)Job FunctionChemistryRequisition ID4774190913
Vacancy expired!