Job Details

ID #43721229
State Massachusetts
City Cambridge
Job type Permanent
Salary USD TBD TBD
Source Apex Systems
Showed 2022-06-30
Date 2022-06-29
Deadline 2022-08-28
Category Et cetera
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Principal Scientist, CNS

Massachusetts, Cambridge, 02138 Cambridge USA

Vacancy expired!

Job#: 1256547

Job Description: Principal Scientist, CNS 1256547

Job Scope & Purpose:

Our client is looking for a Principal Scientist interested in functioning at the cross section of technology and therapeutics. Their team is leveraging the strength of their discovery capabilities to advance the challenging field of CNS therapeutics by utilizing induced pluripotent stem cell (iPSC) technology and patient-derived CNS cell types.

Primary Job Responsibilities:
  • Developing in vitro human CNS disease models (either 2D or 3D) using iPSC-derived from patients
  • Identifying disease-relevant phenotypes from patient-derived CNS cell types and developing robust assays to assess them
  • Validating the gene-editing technology in these disease models to show successful and efficient gene-editing and reversal of disease-relevant phenotypes
  • Interacting and collaborating with gene-editing technology development group, preclinical development group and delivery group to advance the gene-editing technology toward clinical application
  • Supervising an Associate Scientist colleague
  • Manage CROs, interpret and communicate data across functions, and predict timelines and deliverables to internal and external stakeholders
Primary Job Requirements:
  • Education: Ph.D. degree in neuroscience, cell biology, biochemistry, or relevant field with 6+ year of postdoctoral or industry experience.
  • Experience in optimizing 2D or 3D CNS cell-type (neurons, astrocytes and microglia) differentiation from iPSC
  • Experience with high content imaging is desirable
  • Knowledge in the field of CNS diseases
  • Experience in developing assays to measure cellular responses to pathologic processes
  • Highly versatile and team-based mindset
  • Excellent verbal, written communication and presentation skills are essential
About Stratacuity:

Whether you are seeking a career change or simply interested in becoming part of our network, you will appreciate the ethics guiding each Stratacuity team member. We build lasting relationships with exceptional biopharmaceutical talent and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a Stratacuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.

PROVEN SCIENTIFIC PLACEMENT™

Stratacuity is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stratacuity will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact us.

Code: DiscDevt

EEO Employer

Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at or .

Vacancy expired!

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