Vacancy expired!
- Developing in vitro human CNS disease models (either 2D or 3D) using iPSC-derived from patients
- Identifying disease-relevant phenotypes from patient-derived CNS cell types and developing robust assays to assess them
- Validating the gene-editing technology in these disease models to show successful and efficient gene-editing and reversal of disease-relevant phenotypes
- Interacting and collaborating with gene-editing technology development group, preclinical development group and delivery group to advance the gene-editing technology toward clinical application
- Supervising an Associate Scientist colleague
- Manage CROs, interpret and communicate data across functions, and predict timelines and deliverables to internal and external stakeholders
- Education: Ph.D. degree in neuroscience, cell biology, biochemistry, or relevant field with 6+ year of postdoctoral or industry experience.
- Experience in optimizing 2D or 3D CNS cell-type (neurons, astrocytes and microglia) differentiation from iPSC
- Experience with high content imaging is desirable
- Knowledge in the field of CNS diseases
- Experience in developing assays to measure cellular responses to pathologic processes
- Highly versatile and team-based mindset
- Excellent verbal, written communication and presentation skills are essential
Vacancy expired!