Vacancy expired!
Job Description
Eurofins Lancaster Laboratories, Professional Scientific Services is looking for a Principal Scientist - Purification in Horsham, PA to providechromatography, filtration, and statistical expertise in support of commercial manufacturing, process validation and process improvement.
Employee responsibilities include:
- Design and execute experiments in support of the commercial manufacturing process including development, scale up, and troubleshooting/deviations
- Design and execute purification optimization of existing process unit operations and design new unit operations, as needed for 2nd generation manufacturing process
- Support protein purification/isolation and characterization work and perform analytical analysis in support of experiments
- Identify and support improvements to the commercial manufacturing process, focusing on increased product yield or quality improvements, increased efficiency or simplification of operations, risk mitigation, and/or reduced cycle time
- Collaborate with Manufacturing, Quality Control, R&D, Validation, and Quality Assurance on projects and initiatives
- Support the QC unit in laboratory investigations, test plans, out of specification results, and changes in test methods
The Ideal Candidate would possess:
- Experience in a development, process validation, or manufacturing environment is preferred
- Experience with protein chemistry, characterization, and analytical methods, including SDS-PAGE, Western Blot, spectrophotometric assays, and RP-HPLC preferred
- Experience leading technical staff
- Subject matter expertise in protein purification technologies including all modes of column chromatography (ion exchange, hydrophobic interaction, affinity, size exclusion) and filtration (single pass, tangential flow)
- Demonstrated proficiency with interpretation of data, statistical analysis of data, and presenting data in a format that satisfies the objective of the team and drives decisions and/or supports projects
- Experience with experimental design, PAT and QbD principles
- Strong knowledge of cGMP and FDA and international regulations
- Strong knowledge of process technology, development, and validation practices for biopharmaceutical products
- Knowledge of scalable bioprocess purification and filtration strategies
Qualifications
- Bachelor’s degree in Biological Sciences, Bioengineering, or related discipline with 10+ years’ experience working in fermentation process development and/or process validation laboratories OR
- Master’s degree in the above disciplines with 6+ years’ relevant experience (preferred) OR
- PhD in the above disciplines with 4+ years’ relevant experience (preferred)
- Experience working with and supporting commercial and/or clinical manufacturing groups
- Thorough background and knowledge in process development is required particularly in purification and filtration operations
- Authorization to workin the United States indefinitely without restriction or sponsorship
Additional Information
What we offer:- Excellent full time benefits including comprehensive medical coverage, dental, and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
Position is full-time, 8am - 5pm with ocassional overtimerequired.Candidates currently living within a commutable distance of Horsham, PAare encouraged to apply.
As a Eurofins Lancaster Lab PSS employee, you will become part of a company that has received national recognition as a great place to work. We offer excellent full-time benefits including comprehensive medical coverage, life and disability insurance, 401(k) with company match, paid holidays and vacation, personal days, and dental and vision options.
To learn more about Eurofins Lancaster Laboratories, please explore our website www.lancasterlabs.com.
Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.
Vacancy expired!