Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .When you join BMS, you are joining a diverse, high-achieving team united by a common mission.The Pharmaceutical Candidate Optimization organization at Bristol Myers Squibb is a dynamic, multi-disciplinary department that works to discover and optimize new drug candidates. We work across all therapeutic areas and all modalities (small molecules, biotherapeutics, gene and cell therapies and other novel modalities), and engage with all other R&D functions to advance new assets in the BMS portfolio. Our integrated, cross-functional teams apply deep expertise in drug metabolism, pharmacokinetics (DMPK), toxicology, pharmaceutics, and bioanalysis to identify and solve issues, discover high quality drug candidates, and enable their clinical development.Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You'll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.Bristol Myers Squibb (BMS) Drug Metabolism and Pharmacokinetics (DMPK) Department seeks a passionate Scientist to join the Transporter Group. The Transporter Group is a center of excellence serving to understand the roles of transporters in drug ADME, efficacy and toxicity and to de-risk the potential for transporter mediated DDIs. The group supports the BMS portfolio through all stages of discovery and development with stage-appropriate, hypothesis driven, in vitro and in vivo transporter assessments; applying mechanism-based approaches to the quantitative translation of pre-clinical in vitro and in vivo data to clinical findings.In this role, the Scientist will design and conduct various in vitro transporter studies to support the BMS drug discovery and development pipeline. In addition, they will develop novel models and assays for drug transporters to better investigate disposition of drug substrates, which is crucial to our success in optimizing and developing drug candidates and modalities.ResponsibilitiesThe individual will work as part of a dynamic team to design, conduct, and report high-quality in vitro transporter studies utilizing recombinant cell lines, primary cells and membrane vesicles, and to coordinate in vivo studies.Basic Qualifications:Bachelor's Degree 5+ years of academic / industry experienceor Master's Degree 3+ years of academic / industry experienceor PhD No experience requiredPreferred Qualifications:
PhD degree in biology, toxicology, pharmacology, or related major, with no experience required, Master's degree with 3+ years of experience in the ADMET field, or Bachelor's degree with 5+ years relevant ADMET experience
Working knowledge of drug absorption, distribution, metabolism, excretion and transporters
Experience with mammalian cell culture and in vitro transporter assays in recombinant cell lines, primary hepatocytes and/or membrane vesicles
Ability to independently design experiments and deliver data in a timely manner, including authoring of research reports for regulatory submission
Ability to analyze and summarize data using tools such as Excel, Graphpad, and PowerPoint
Excellent oral and written communication skills, and track record of working collaboratively in a team environment
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing CareersWith a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.Company: Bristol-Myers SquibbReq Number: R1583971Updated: 2024-07-31 01:50:15.995 UTCLocation: Princeton-NJBristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.